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Due to technical issues on the email address (, we kindly ask to who applied for any scholarship before January 11th, to REAPPLY. The new deadline is January 25th.


Call for Applications for a PhD Scholarship at Hovione (M/F)

Ref: Tetracyclines/BDE/01


Hovione FarmaCiencia SA (Hovione) is a Portuguese company specialized in Health Sciences, dedicated to the research, development and production of Active Pharmaceutical Substances (APIs), and drug products for pulmonary inhalation and oral delivery. Hovione innovates and leads worldwide in the field of pharmaceutical chemistry, as demonstrated by about 400 worldwide patents. The products and procedures developed at Hovione meet the high standards of compliance established by the International Conference Harmonization (ICH), Food and Drug Administration (FDA) and Health Authorities of European countries and Japan.

As an integral part of Hovione's Innovation Strategy, the PhD program Design and development of selective synthesis of tetracycline derivatives using computational modeling and flow chemistry methodologies using micro-reactors and process control analytical tools was created and awarded a PhD (BDE) scholarship.

Thus, under the terms of the ”Estatuto do Bolseiro de Investigação Ciêntifica”, approved by “Lei nº 40/2004” amended by “Decreto-Lei nº 202/2012”, of 27th August, and amended by “Decreto-Lei nº. 233/2012, of 29th October and by “lei nº12/2013, of 29th January and “Decreto-Lei nº. 89/2013”, of 9th July (Research Grants Regulation of the Foundation for Science and Technology (FCT)), now in force, a call for the selection of scholars and grant of an individual scholarship is open:



The present call is open to a PhD (BDE) Scholarship under the conditions and characteristics set forth in Article 6 of the FCT Research Grant Regulation in force in 2017.






Masters in Chemistry, Chemical Engineering or Pharmaceutical engineering (preferential) with a minimum grade of 16 may apply for this call. Preference will be given to English fluent candidates with proven experience in lab work in synthetic organic chemistry (preferentially in an industrial environment), and in flow chemistry (micro-reactors and/or tubular reactors) an analytical support systems. Preference will also be given candidates with proven experience in the design of experiments, multivariate analysis and computer modeling software and qualifications in patent writing areas related to the detailed work plan below and fluent in English. And revision. Personal characteristics: Enthusiasm, organization and objectivity; Analytical sense (attention to detail); Sense of responsibility and ethics; Analytic and pragmatic problem solving attitude; Good interpersonal skills.



The activity of the scholar should focus on the following tasks: 

State of the art assessment and identification of key synthetic steps in the synthesis of antibiotics of the 3rd generation tetracyclines with selectivity and stability problems. Selection and assembly of equipment and execution of compatibility and feasibility tests.

Development of integrated development methodologies of innovative processes applying computational modelling, statistical design of experiments and flow chemistry, using micro-reactors supported with process control analytical tools.

Optimization of identified processes towards the reduction of cost and environmental impact (eliminating steps of synthesis and purification) from the production processes, increasing operational safety.

Assessment of viability, sustainability and economical interest as well as intellectual property protection of the design space of the developed processes.



The implementation of the program will take place at Hovione's premises, in close collaboration with Faculdade de Farmácia da Universidade de Lisboa.



The scientific supervisors of the program will be Professor Carlos Afonso (FF-UL) and Rudi Oliveira PhD (Hovione).



The scholarship has a maximum duration of 3.5 years; it is granted on a full-time basis and is awarded annually, for periods of 12 consecutive months and automatically renewable, unless under the applicable legislation the scholar fails to fulfill his / her assigned duties. The scholarship is scheduled to start in February 2018 on an exclusive basis.



This call is addressed to anyone who is eligible to participate in the Program.



The call t is open between 2nd and 25th January 2018.



Applications must be completed through a motivation letter to, mentioning the Program and this announcement, together with the following documents: Letter of Motivation, detailed Curriculum Vitae of the applicant [proving the above mentioned requirements] copy of relevant diploma, a valid email address and a contact telephone number, contact details of 2 persons as referrals  and other documents which the applicant considers relevant for the evaluation of his / her application.

Only applications received until 17:00 on 25th January  2018 will be considered.

Alternative email address



The selection methods are as follows:

  1. Scientific merit taking into account the curriculum vitae of the candidate, degree/masters grade (minimum 14/20), participation in research projects, suitability of the candidate's profile to the Program theme and candidate experience in the Program theme;
  2. Level of English;
  3. Letter of motivation;
  4. Interview.

Each item will be scored on a scale of 0-20, with the following weights: Curriculum vitae and experience (40%), English (10%), motivation letter (10%) and interview (40%).

The evaluation of the applications will be carried out by the Evaluation Panel defined in accordance with Article 17 of the FCT Research Grants Regulation.



The evaluation panel comprises the Hovione's Scientific Advisors panel, Hovione Innovation Manager and Hovione HR Business Partner.



The results of the evaluation, presented in descending order, are published through the Hovione website and sent to the applicants within the deadline set in Article 18 of the FCT Research Grants Regulation.



The scholarship has a value of € 980, which is in accordance with the table of values for scholarships awarded directly by FCT, I.P. (, and is 100% funded by Hovione. The scholarship payment will be made monthly.

The tuition fees of the Academic Institution will also be paid entirely by Hovione.



Only requests made by e-mail to or the alternative email address will be considered.